1253909-20-4

Basic information

• Product Name: 1-(5-iodo-2-methylphenyl)-4-(toluene-4-sulfonyl)piperazine
• Synonyms: 1-(5-iodo-2-methylphenyl)-4-(toluene-4-sulfonyl)piperazine
• CAS NO: 1253909-20-4
• Molecular Weight: 456.347
• Mol File: 1253909-20-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: 1-(5-iodo-2-methylphenyl)-4-(toluene-4-sulfonyl)piperazine(CAS DataBase Reference)
• NIST Chemistry Reference: 1-(5-iodo-2-methylphenyl)-4-(toluene-4-sulfonyl)piperazine(1253909-20-4)
• EPA Substance Registry System: 1-(5-iodo-2-methylphenyl)-4-(toluene-4-sulfonyl)piperazine(1253909-20-4)

Safety Data

• Hazardous Substances Data: 1253909-20-4(Hazardous Substances Data)

Upstream product

• 83863-33-6 5-iodo-o-toluidine 
• 42137-88-2 N,N-bis(2-chloroethyl)-p-toluenesulfonamide 

Downstream Products

• 1253909-19-1 1-[5-(3-difluoromethoxybenzenesulfonyl)-2-methylphenyl]-4-(toluene-4-sulfonyl)piperazine 

Relevant articles and documents

N-PHENYL-(PIPERAZINYL OR HOMOPIPERAZINYL)-BENZENESULFONAMIDE OR BENZENESULFONYL-PHENYL-(PIPERAZINE OR HOMOPIPERAZINE) COMPOUNDS SUITABLE FOR TREATING DISORDERS THAT RESPOND TO MODULATION OF THE SEROTONIN 5-HT6 RECEPTOR

The present invention relates to N-phenyl-(piperazinyl or homopiperazinyl)- benzenesulfonamide or benzenesulfonyl-phenyl-(piperazine or homopiperazine) compounds,pharmaceutical compositions containing them, and their use in therapy. The compounds possess valuable therapeutic properties and are particularly suitable for treating diseases that respond to modulation of the serotonin 5-HT6 receptor. wherein X is a bond or a group N-R4; R1 is hydrogen or methyl; R2 is hydrogen or methyl; R3 is hydrogen, C1-C3 alkyl, fluorine, C1-C2 alkoxy or fluorinated C1-C2 alkoxy; R4 is hydrogen, C1-C4 alkyl, C3-C4 cycloalkyl, or C3-C4 cycloalkyl-CH2-; R5 is hydrogen, fluorine, chlorine, C1-C2 alkyl, fluorinated C1-C2 alkyl, C1-C2 alkoxy or fluorinated C1-C2 alkoxy; R6 is hydrogen, fluorine or chlorine; and n is 1 or 2.