1253933-66-2Relevant academic research and scientific papers
Synthesis, characterization and in vitro antimicrobial studies of new 2, 3-disubstituted quinazolin-4(3H) ones of 2-[2-(2, 6-dichlorophenyl)amino] phenyl acetic acid
Patel, Navin B.,Shaikh, Asif R.
experimental part, p. 929 - 936 (2010/10/18)
2-[2-(2, 6-Dichlorophenyl)amino]phenylmethyl-3-{4-[(substituted phenyl)amino]-l, 3-oxazol-2-yl}-]-6-bromoquinazo- lin-4(3H)ones 5a-o have been synthesized from the lead molecule 2-[(2, 6-dichlorophenyl)amino]phenyl acetic acid 1, via carboxamide 4. Compound 4 on cyclization with substituted phenyl acetamide a-o gave desired compounds 5a-o. The title compounds have been characterized by elemental analysis, IR, 1H NMR and 13C NMR spectral data. All the compounds have been screened for antibacterial and antifungal activity.
