(+/-)-N(α),N(ε)-Diphthaloyl-4-oxalysin is a synthetic chemical compound that serves as a potent inhibitor of the enzyme dipeptidyl peptidase IV (DPP-IV). This enzyme plays a crucial role in the regulation of glucose homeostasis by inactivating glucagon-like peptide-1 (GLP-1), a hormone that stimulates insulin secretion and inhibits glucagon release. By inhibiting DPP-IV, (+/-)-N(α),N(ε)-Diphthaloyl-4-oxalysin can potentially enhance the action of GLP-1, thereby improving glucose control in conditions such as type 2 diabetes. The compound is characterized by its ability to bind to the active site of DPP-IV, thereby preventing the enzyme from cleaving GLP-1 and other substrates. This inhibition can lead to increased levels of active GLP-1 in the bloodstream, which may contribute to better management of blood sugar levels. The compound's structure and mechanism of action make it a subject of interest in the development of therapeutic strategies for metabolic disorders.
The CAS Registry Mumber 1254-18-8 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 1,2,5 and 4 respectively; the second part has 2 digits, 1 and 8 respectively. Calculate Digit Verification of CAS Registry Number 1254-18: (6*1)+(5*2)+(4*5)+(3*4)+(2*1)+(1*8)=58 58 % 10 = 8 So 1254-18-8 is a valid CAS Registry Number.