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1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine is a complex chemical compound that features a piperidine ring fused with a piperazine ring. It also includes a phenyl ring with a methoxy and a nitro group, as well as a methyl group. 1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine may possess pharmacological properties due to the presence of piperidine and piperazine rings, which are common in pharmaceuticals and drug development for various medical conditions. Further research is required to ascertain its specific characteristics and potential applications.

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  • 1254058-33-7 Structure
  • Basic information

    1. Product Name: 1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine
    2. Synonyms:
    3. CAS NO:1254058-33-7
    4. Molecular Formula:
    5. Molecular Weight: 334.418
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 1254058-33-7.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: 488.9±45.0 °C(Predicted)
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: 1.195±0.06 g/cm3(Predicted)
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: 1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine(CAS DataBase Reference)
    10. NIST Chemistry Reference: 1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine(1254058-33-7)
    11. EPA Substance Registry System: 1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine(1254058-33-7)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 1254058-33-7(Hazardous Substances Data)

1254058-33-7 Usage

Uses

As the provided materials do not specify any particular uses for 1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine, it is not possible to list its applications based on the information given. However, given its structure, it may be explored for potential use in the pharmaceutical industry, similar to other compounds containing piperidine and piperazine rings. Possible applications could include:
Used in Pharmaceutical Industry:
1-[1-(2-methoxy-4-nitrophenyl)piperidin-4-yl]-4-methylpiperazine could be used as a pharmaceutical compound for [specific medical condition] due to its structural features that are common in drug development.
Without specific details on its applications, it is recommended to conduct further research to explore its potential uses in various industries.

Check Digit Verification of cas no

The CAS Registry Mumber 1254058-33-7 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,4,0,5 and 8 respectively; the second part has 2 digits, 3 and 3 respectively.
Calculate Digit Verification of CAS Registry Number 1254058-33:
(9*1)+(8*2)+(7*5)+(6*4)+(5*0)+(4*5)+(3*8)+(2*3)+(1*3)=137
137 % 10 = 7
So 1254058-33-7 is a valid CAS Registry Number.

1254058-33-7Downstream Products

1254058-33-7Relevant articles and documents

WEE1 inhibitors as well as preparation and application thereof

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Paragraph 0741-0747, (2020/10/14)

The invention relates to WEE1 inhibitors as well as preparation and application thereof. The present invention relates to compounds of formula (I), or pharmaceutically acceptable salts, solvates, polymorphs or isomers thereof, and their use in the preparation of medicaments for the treatment of diseases associated with WEE1 activity.

SUBSTITUTED DIAMINO HETEROCYCLIC CARBOXAMIDE COMPOUND AND A COMPOSITION CONTAINING THE COMPOUND AND USE THEREOF

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Paragraph 0165-0166; 0171, (2020/12/07)

A substituted amino heterocyclic carboxamide compound as represent by formula (Φ), or a pharmaceutically acceptable salt, a prodrug, a hydrate or a solvent compound, a crystal form, a stereoisomer or an isotopic variant of the compound, and a pharmaceutical composition thereof, and the use thereof as an FLT3/AXL kinase inhibitor for treating acute myelocytic leukemia.

Discovery of N-{2-methoxy-4-[4-(4-methylpiperazin-1-yl)piperidin-1-yl]phenyl}-N′-[2-(propane-2-sulfonyl)phenyl]-1,3,5-triazine-2,4-diamine (ASP3026), a potent and selective anaplastic lymphoma kinase (ALK) inhibitor

Iikubo, Kazuhiko,Kondoh, Yutaka,Shimada, Itsuro,Matsuya, Takahiro,Mori, Kenichi,Ueno, Yoko,Okada, Minoru

, p. 251 - 262 (2018/03/13)

Anaplastic lymphoma kinase (ALK) is a validated therapeutic target for treating echinoderm microtubule- associated protein-like 4 (EML4)-ALK positive non-small cell lung cancer (NSCLC). We synthesized a series of 1,3,5-triazine derivatives and identified ASP3026 (14a) as a potent and selective ALK inhibitor. In mice xenografted with NCI-H2228 cells expressing EML4-ALK, once-daily oral administration of 14a demonstrated dose-dependent antitumor activity. Here, syntheses and structure-activity relationship (SAR) studies of 1,3,5-triazine derivatives are described.

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