1254120-31-4

Basic information

• Product Name: C₂₆H₃₀OSi
• Synonyms: C₂₆H₃₀OSi
• CAS NO: 1254120-31-4
• Molecular Weight: 386.609
• Mol File: 1254120-31-4.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₆H₃₀OSi(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₆H₃₀OSi(1254120-31-4)
• EPA Substance Registry System: C₂₆H₃₀OSi(1254120-31-4)

Safety Data

• Hazardous Substances Data: 1254120-31-4(Hazardous Substances Data)

Upstream product

• 917-54-4 methyllithium 
• 146861-22-5 2(S)-<(tert-butyldiphenylsilyl)oxy>-3-phenylpropanal 

Downstream Products

• 6052-66-0 (S)-(+)-1-phenylbut-3-en-2-ol 

Relevant articles and documents

Enantioselective synthesis of cyclic, quaternary oxonitriles

Quaternary oxonitriles are stereoselectively generated from the union of five-, six-, and seven-membered 2-chloroalkenecarbonitriles with chiral alcohols via a Claisen rearrangement. The strategy rests on a new conjugate addition-elimination of allylic alkoxides to 2-chlorocycloalkenecarbonitriles to afford substituted 2-alkoxyalkenenitriles. Subsequent thermolysis unmasks a cyclic oxonitrile while selectively forming a new quaternary center with enantiomeric ratios typically greater than 9:1. The overall alkylation strategy addresses the challenge of enantioselectively generating hindered, quaternary centers while simultaneously installing ketone, nitrile, and olefin functionalities.