125414-29-1

Basic information

• Product Name: (S)-1-((R)-2-Trichloromethyl-4,5-dihydro-oxazol-4-yl)-butan-1-ol
• Synonyms: (S)-1-((R)-2-Trichloromethyl-4,5-dihydro-oxazol-4-yl)-butan-1-ol
• CAS NO: 125414-29-1
• Molecular Weight: 260.548
• Mol File: 125414-29-1.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (S)-1-((R)-2-Trichloromethyl-4,5-dihydro-oxazol-4-yl)-butan-1-ol(CAS DataBase Reference)
• NIST Chemistry Reference: (S)-1-((R)-2-Trichloromethyl-4,5-dihydro-oxazol-4-yl)-butan-1-ol(125414-29-1)
• EPA Substance Registry System: (S)-1-((R)-2-Trichloromethyl-4,5-dihydro-oxazol-4-yl)-butan-1-ol(125414-29-1)

Safety Data

• Hazardous Substances Data: 125414-29-1(Hazardous Substances Data)

Upstream product

• 92418-71-8 (2R,3R)-2,3-epoxy-1-hexanol 

Downstream Products

• 125414-62-2 (4R,5S)-4-Hydroxymethyl-5-propyl-oxazolidin-2-one 

Relevant articles and documents

Amino Acids and Peptides; 70. Optically Active α-Amino Acids, N-Boc-Aminoaldehydes and α-Amino-β-hydroxy Acids from 2,3-Epoxy Alcohols

Trichloroacetimidic esters of 2,3-epoxy alcohols are transformed into oxazolines 5 and dihydrooxazines 6, respectively, depending on the structure of the educts and the catalyst.The five-membered ring compounds 5 are transformed into erythro-α-amino-β-hydroxy acids (60-70percent from epoxy alcohols) via axazolidinones 11, 12, and 13. α-Amino acids and α-substituted α-amino acids 10 as well as the corresponding aldehydes 9 are obtained from the dihydrooxazines 6 (50-60percent from epoxy alcohols).