1254177-46-2 Usage
Nitrile derivative
2-(4-nitrophenyl)-3-tolylpropanenitrile 2-(4-nitrophenyl)-3-p-tolylpropanenitrile is a nitrile derivative of the compound 2-(4-nitrophenyl)-3-tolylpropanenitrile, meaning it has a cyano group (CN) attached to the molecule.
Bright yellow solid at room temperature 2-(4-nitrophenyl)-3-p-tolylpropanenitrile is a bright yellow solid at room temperature, indicating its physical appearance and state.
Used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals 2-(4-nitrophenyl)-3-p-tolylpropanenitrile is often used as an intermediate in the synthesis of various pharmaceuticals and agrochemicals, indicating its importance in the production of these products.
Used in research and development settings 2-(4-nitrophenyl)-3-p-tolylpropanenitrile is most commonly used in research and development settings, indicating its role in scientific studies and product development.
Potentially harmful if ingested, inhaled, or comes into contact with skin or eyes It is important to handle and store 2-(4-nitrophenyl)-3-p-tolylpropanenitrile with care, as it may be harmful if ingested, inhaled, or comes into contact with skin or eyes, indicating its potential health risks.
Check Digit Verification of cas no
The CAS Registry Mumber 1254177-46-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,4,1,7 and 7 respectively; the second part has 2 digits, 4 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1254177-46:
(9*1)+(8*2)+(7*5)+(6*4)+(5*1)+(4*7)+(3*7)+(2*4)+(1*6)=152
152 % 10 = 2
So 1254177-46-2 is a valid CAS Registry Number.
1254177-46-2Relevant articles and documents
Solvent-free 2-p-nitrophenyl-3-aryl propionitrile and preparation method thereof
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Paragraph 0058-0062, (2018/04/01)
The invention discloses a solvent-free 2-p-nitrophenyl-3-aryl propionitrile and a preparation method thereof. The preparation method comprises the following steps: adding 4-nitrophenylacetonitrile, aromatic aldehyde, alkali and dihydropyridine ester into a reaction test tube and performing stirring reaction; performing column chromatography to obtain the product 2-p-nitrophenyl-3-aryl propionitrile, wherein the stationary phase used according to the column chromatography is a silica gel column. The problems that the solvent in the prior art is not economic and is not environmentally friendly and the reaction time is long are solved, and the technical gap that the 2-p-nitrophenyl-3-aryl propionitrile is prepared by taking the dihydropyridine ester as a hydrogen source under the solvent-free condition is remedied; by a one-pot method, Knoevenagel and reduction two-step reaction are connected in series, the reaction steps are simplified, and a target product can be obtained efficiently. The dihydropyridine ester serves as the hydrogen source, so compared with the traditional hydrogen source, the hydrogen source has the advantages of no toxicity, mild reaction condition and high chemical selectivity.
