1254199-66-0

Basic information

• Product Name: [(S)-4-(3-amino-phenyl)-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester
• Synonyms: [(S)-4-(3-amino-phenyl)-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester
• CAS NO: 1254199-66-0
• Molecular Weight: 332.403
• Mol File: 1254199-66-0.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: [(S)-4-(3-amino-phenyl)-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester(CAS DataBase Reference)
• NIST Chemistry Reference: [(S)-4-(3-amino-phenyl)-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester(1254199-66-0)
• EPA Substance Registry System: [(S)-4-(3-amino-phenyl)-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester(1254199-66-0)

Safety Data

• Hazardous Substances Data: 1254199-66-0(Hazardous Substances Data)

Upstream product

• 887913-52-2 (methylamino)thioxomethylcarbamic acid t-butyl ester 
• 1254199-40-0 (S)-3-((R)-2-methyl-propane-2-sulfinylamino)-3-(3-nitro-phenyl)-butyric acid methyl ester 
• 1254199-37-5 (R)-2-methyl-N-(1E)-(1-(3-nitrophenyl)ethylidene)propane-2-sulfinamide 
• 4248-19-5 tert-butyl carbazate 
• 1213190-97-6 (S)-3-amino-3-(3-nitro-phenyl)-butyric acid methyl ester 
• 121-89-1 3-Nitroacetophenone 
• 1254199-50-2 [(S)-1,4-dimethyl-4-(3-nitro-phenyl)-6-oxo-1,4,5,6-tetrahydro-pyrimidin-2-yl]-carbamic acid tert-butyl ester 

Downstream Products

• 1254196-70-7 S-methyl-thiophene-1-carboxylic acid [3-((S)-2-amino-1,4-dimethyl-6-oxo-1,4,5,6-tetrahydro-pyrimidin-4-yl)phenyl]amide hydrochloride 

Relevant articles and documents

1,4,5,6-TETRAHYDRO-PYRIMIDIN-2-YLAMINE COMPOUNDS

This invention relates to compounds of the formula wherein R1 to R9 are as described below, or to pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors and can be used as medicaments for the therapeutic and/

DIHYDROPYRIMIDINONES FOR USE AS BACE2 INHIBITORS

This invention relates to dihydropyrimidinones of the formula (I), wherein X and R1 to R7 are as defined in the description and in the claims, as well as pharmaceutically acceptable salts thereof. These compounds are BACE2 inhibitors