1254221-40-3Relevant academic research and scientific papers
Palladium-Catalyzed Synthesis of Tetrasubstituted Olefins by Triple Domino Process
Naveen, Kanagaraj,Nikson, Savariyappan Albert,Perumal, Paramasivan Thirumalai
supporting information, p. 2407 - 2413 (2017/07/22)
An efficient, highly regio- and stereoselective protocol for the synthesis of tetrasubstituted olefins was developed to take place by a palladium(0)-catalyzed triple domino process. It involves the formation of three new C?C bonds through double carbopalladation and C?H activation across 2-bromoaryl alkynyl biaryls/heteroaryls with norbornene. This method is practically simple with broad substrate scope and tolerates a wide range of substituents. The products bearing 9H-pyrrolo[1,2-a]indole motifs reveal intriguing solid state fluorescence properties and thus form a new class of aggregation induced emission (AIE) fluorophores. (Figure presented.).
C-H bond functionalization in the synthesis of fused 1,2,3-triazoles
Panteleev, Jane,Geyer, Karolin,Aguilar-Aguilar, Angelica,Wang, Letian,Lautens, Mark
supporting information; experimental part, p. 5092 - 5095 (2011/02/22)
A highly modular approach to fused 1,2,3-triazoles has been developed featuring a one-pot procedure combining copper(I) catalyzed azide-alkyne cycloaddition and palladium-catalyzed C-H bond functionalization. A class of structurally unique heterocycles was synthesized in good yields.
