1254331-83-3Relevant academic research and scientific papers
Unified Strategy for 1,5,9- and 1,5,7-Triols via Configuration-Encoded 1,5-Polyol Synthesis: Preparation and Coupling of C15-C25 and C26-C40 Fragments of Tetrafibricin
Friedrich, Ryan M.,Bell, Jay Q.,Garcia, Alfredo,Shen, Zican,Friestad, Gregory K.
, p. 13650 - 13669 (2018/11/23)
Diverse classes of natural products contain chiral 1,5,9- and 1,5,7-triol stereotriads, including the novel fibrinogen receptor antagonist tetrafibricin. Biological activities associated with compounds containing these motifs warrant targeted synthetic st
Versatile configuration-encoded strategy for rapid synthesis of 1,5-polyol stereoisomers
Friestad, Gregory K.,Sreenilayam, Gopeekrishnan
supporting information; experimental part, p. 5016 - 5019 (2010/12/29)
The isolated stereogenic centers of 1,5-polyol-containing natural products present challenges to synthesis and structure determination. To address this problem, a configuration-encoded strategy defines each configuration within a simple 4-(arylsulfonyl)bu
