1254356-81-4Relevant articles and documents
Stereoselective synthesis of 2,4,5-trisubstituted piperidines via radical cyclization
Ragoussi, Maria-Eleni,Walker, Stephen M.,Piccanello, Andrea,Kariuki, Benson M.,Horton, Peter N.,Spencer, Neil,Snaith, John S.
supporting information; experimental part, p. 7347 - 7357 (2011/02/16)
A novel approach to 2,4,5-trisubstituted piperidines is reported, involving the 6-exo cyclization of stabilized radicals onto α,β-unsaturated esters. Only two of the four possible diastereoisomers are observed, with diastereomeric ratios ranging from 3:2