1254475-90-5Relevant academic research and scientific papers
Intramolecular Activation of Enones by Electrophilic Phosphinidene Complexes to Construct 2-Phosphafurans
Duan, Zheng,Li, Hong,Tian, Rongqiang
, p. 767 - 770 (2022/02/07)
Herein, we report a facile and highly atom-economic approach to 2-phosphafurans by using simple 2-chloroethylphosphine and acetylenic ketones. The key step of this protocol utilizes the Lewis acidity of electrophilic phosphinidenes to induce an intramolecular cyclization with enones. Dearomative hetero-Diels-Alder reactions of 2-phosphafurans provide two series of bicyclic phosphacycles. This rare synthetic application of Lewis acidity of electrophilic phosphinidene complexes represents a new frontier of phosphinidene chemistry.
Synthesis and chemistry of 2-phosphafurans
Duffy, Matthew P.,Lin, Yuhan,Ho, Feny,Mathey, Francois
, p. 5757 - 5758 (2011/01/12)
The reaction between (chlorophosphinidene)pentacarbonyltungsten and benzylideneacetophenone affords a [4 + 1] adduct whose dehydrochlorination by N-methylimidazole affords a 2-phosphafuran complex. Upon further reaction, the phosphafuran is displaced from
