1254732-06-3

Upstream product

• 619-42-1 4-methoxycarbonylphenyl bromide 
• 1254730-80-7 8-[(2,6-diethoxy-4'-fluorobiphenyl-4-yl)methyl]-2,8-diazaspiro[4.5]decan-3-one 

Downstream Products

• 1254732-07-4 methyl 4-{8-[(2,6-diethoxy-4'-fluorobiphenyl-4-yl)methyl]-3-oxo-2,8-diazaspiro[4.5]dec-2-yl}benzoate trifluoroacetic acid 

Relevant academic research and scientific papers

SUBSTITUTED SPIROCYCLIC AMINES USEFUL AS ANTIDIABETIC COMPOUNDS

Substituted spirocyclic amines of structural formula I are selective antagonists of the somatostatin subtype receptor 5 (SSTR5) and are useful for the treatment, control or prevention of disorders responsive to antagonism of SSTR5, such as Type 2 diabetes, insulin resistance, lipid disorders, obesity, atherosclerosis, metabolic syndrome, depression, and anxiety.