1254754-78-3Relevant academic research and scientific papers
Synthesis and DNA cleavage evaluation of epoxypiperidine derivatives bearing a dehydroamino acid unit
Yamaguchi, Takao,Kawada, Yuji,Obika, Satoshi,Imanishi, Takeshi,Miyashita, Kazuyuki
experimental part, p. 8181 - 8188 (2010/11/17)
Epoxypiperidine derivatives bearing a dehydroamino acid unit were designed and synthesized as novel DNA alkylating agents based on the structure of azinomycins. A relaxation assay of plasmid DNA revealed that the epoxypiperidine derivative 3 has a DNA cle
