125482-07-7

Usage

Uses

Used in Food Industry:
Benzoic acid, 3,5-bis(decyloxy)is used as a food preservative for its ability to inhibit the growth of bacteria and fungi, ensuring the freshness and safety of food products.
Used in Flavoring Industry:
Benzoic acid, 3,5-bis(decyloxy)is used as a flavoring agent, enhancing the taste and aroma of various food and beverage products.
Used in Cosmetic Industry:
Benzoic acid, 3,5-bis(decyloxy)is used in cosmetic products for its antimicrobial properties, helping to prevent the growth of harmful microorganisms and ensuring product safety and efficacy.
Used in Pharmaceutical Industry:
Benzoic acid, 3,5-bis(decyloxy)is utilized in pharmaceutical products for its antimicrobial properties, contributing to the prevention and treatment of infections.
Used in Material Science:
Benzoic acid, 3,5-bis(decyloxy)has potential applications in the development of new materials, such as polymers and coatings, due to its unique chemical structure and properties.
Used in Organic Synthesis:
Benzoic acid, 3,5-bis(decyloxy)serves as a building block for the synthesis of more complex organic compounds, contributing to the advancement of organic chemistry and the development of novel pharmaceuticals and specialty chemicals.

Upstream product

• 112-29-8 1-bromo dodecane 
• 99-10-5 3,5-Dihydroxybenzoic acid 
• 2150-44-9 1-carbomethoxy-3,5-dihydroxybenzene 
• 125482-06-6 methyl 3,5-bis(decyloxy)benzoate 

Downstream Products

• 1026929-44-1 3,5-Bis-decyloxy-benzoyl azide 
• 122060-82-6 3,5-didecyloxybenzoyl chloride 

Relevant academic research and scientific papers

One-Component Multifunctional Sequence-Defined Ionizable Amphiphilic Janus Dendrimer Delivery Systems for mRNA

Efficient viral or nonviral delivery of nucleic acids is the key step of genetic nanomedicine. Both viral and synthetic vectors have been successfully employed for genetic delivery with recent examples being DNA, adenoviral, and mRNA-based Covid-19 vaccines. Viral vectors can be target specific and very efficient but can also mediate severe immune response, cell toxicity, and mutations. Four-component lipid nanoparticles (LNPs) containing ionizable lipids, phospholipids, cholesterol for mechanical properties, and PEG-conjugated lipid for stability represent the current leading nonviral vectors for mRNA. However, the segregation of the neutral ionizable lipid as droplets in the core of the LNP, the "PEG dilemma", and the stability at only very low temperatures limit their efficiency. Here, we report the development of a one-component multifunctional ionizable amphiphilic Janus dendrimer (IAJD) delivery system for mRNA that exhibits high activity at a low concentration of ionizable amines organized in a sequence-defined arrangement. Six libraries containing 54 sequence-defined IAJDs were synthesized by an accelerated modular-orthogonal methodology and coassembled with mRNA into dendrimersome nanoparticles (DNPs) by a simple injection method rather than by the complex microfluidic technology often used for LNPs. Forty four (81%) showed activity in vitro and 31 (57%) in vivo. Some, exhibiting organ specificity, are stable at 5 °C and demonstrated higher transfection efficiency than positive control experiments in vitro and in vivo. Aside from practical applications, this proof of concept will help elucidate the mechanisms of packaging and release of mRNA from DNPs as a function of ionizable amine concentration, their sequence, and constitutional isomerism of IAJDs.

Screening Libraries of Amphiphilic Janus Dendrimers Based on Natural Phenolic Acids to Discover Monodisperse Unilamellar Dendrimersomes

Natural, including plant, and synthetic phenolic acids are employed as building blocks for the synthesis of constitutional isomeric libraries of self-assembling dendrons and dendrimers that are the simplest examples of programmed synthetic macromolecules.

Dicarbonyl chelates from 1-cymantrenylalkylamides with the dendrite structure: formation, photochromism, and kinetics of dark reaction with carbon monoxide

Photolysis of carboxamides of the dendrite structure with aminomethyland 1-aminoethylcymantrenes leads to the formation of six-membered dicarbonyl chelates with the Mn—O bond which are stable in solutions. The chelates in the reversed dark reaction with carbon monoxide give the starting tricarbonyl complexes. The formation of the chelates and their dark reaction are accompanied by the reversible change of color by the compounds. The rate determining step of the thermal reaction of chelates with CO is a chelate ring opening with the ligand substitution by the SN1 mechanism. A possibility of solvent-free photoinduced ligand-exchange reaction in a number of cymantrene derivatives was demonstrated.

N-SUBSTTTUTED ANILINES, INHIBITORS OF PHOSPHOLIPASES A2

Compounds of the formula wherein R1, R2, R3, R4, Rs, Re, R7, R8, n, m, o, p and q are as hereinafter set forth, and, when R2 is hydrogen, pharmaceutically acceptable salts thereof with bases,are described. The compounds of formula 1 are potent inhibitors of phospholipases A2 (PLA2's) and are therefore useful in the treatment of inflammatory diseases, such as psosiasis, inflammatory bowel disease, asthma, allergy, arthritis, dermatitis, gout, pulmonary disease, myocardial ischemia/reperfusion, and trauma induced inflammation, such as spinal cord injury