125483-57-0 Usage
Description
Benzyl 1-Aminocyclobutanecarboxylate 4-Methylbenzenesulfonate, also known as BAC, is an organic compound that serves as a crucial intermediate in the synthesis of various pharmaceutical compounds. It is characterized by its unique chemical structure, which allows it to participate in multiple chemical reactions, making it a versatile building block in the field of medicinal chemistry.
Uses
Used in Pharmaceutical Industry:
Benzyl 1-Aminocyclobutanecarboxylate is used as a reactant for the preparation of [N-(p-phenoxyphenylsulfonyl)-N-(carboxyethyl)amino]cyclobutanecarbohydroxamic acid derivatives. These derivatives act as matrix metalloproteinase (MMP) inhibitors, which are essential in the treatment of various diseases. MMPs are enzymes that play a significant role in the breakdown of extracellular matrix in normal biological processes, such as tissue remodeling and wound healing. However, their overexpression has been associated with the progression of several diseases, including cancer, cardiovascular diseases, and neurodegenerative disorders. By inhibiting MMPs, BAC-derived compounds can potentially slow down or prevent the progression of these diseases, offering a promising therapeutic approach for patients.
Check Digit Verification of cas no
The CAS Registry Mumber 125483-57-0 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,4,8 and 3 respectively; the second part has 2 digits, 5 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 125483-57:
(8*1)+(7*2)+(6*5)+(5*4)+(4*8)+(3*3)+(2*5)+(1*7)=130
130 % 10 = 0
So 125483-57-0 is a valid CAS Registry Number.
125483-57-0Relevant articles and documents
Cyclobutyl-aryloxyarylsulfonylamino hydroxamic acid derivatives
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, (2008/06/13)
A compound of the formula ???wherein Y is as defined above, useful in the treatment of arthritis or cancer and other diseases involving selective inhibition of matrix metalloproteinase-13.
