1254836-16-2

Upstream product

• 3587-60-8 Benzyloxymethyl chloride 
• 6153-44-2 methyl orotate 

Downstream Products

• 1254836-15-1 3-(benzyloxymethyl)-2,6-dioxo-N-(2-(trifluoromethoxy)benzyl)-1,2,3,6-tetrahydropyrimidine-4-carboxamide 
• 1254837-98-3 3-(benzyloxymethyl)-N-(4-bromo-2-(trifluoromethoxy)benzyl)-2,6-dioxo-1,2,3,6-tetrahydropyrimidine-4-carboxamide 

Relevant academic research and scientific papers

2,6-DIOXO-1,2,3,6-TETRAHYDROPYRIMIDINE-4-CARBOXAMIDES

Disclosed are sEH inhibitors of formula (I), wherein the variables are as defined herein, as well as pharmaceutical compositions, kits, and articles of manufacture that contain such compounds. Also disclosed are methods and intermediates for making the compounds and the use of such compounds to treat various disorders, diseases, and conditions associated with sEH.