1254977-23-5Relevant articles and documents
Iodine/Et3SiH: A novel reagent system for the synthesis of 3-aryl-1H-indenes from 1,3-diaryl propargyl alcohols
Reddy, B.V. Subba,Reddy, B. Brahma,Rao, K.V. Raghavendra,Yadav
, p. 5697 - 5700 (2010)
1,3-Diaryl propargyl alcohols undergo smooth intramolecular Friedel-Crafts cyclization with triethylsilane in the presence of 10 mol % iodine 3-aryl-1H-indene derivatives in good yields in short reaction times. This is the first example on the synthesis of substituted indenes from 1,3-diaryl propargyl alcohols. The use of inexpensive and readily available molecular iodine makes this method quite simple, more convenient, and practical.