125519-47-3 Usage
Chemical class
Sesquiterpene lactone
Source
Latex of Lactuca species, such as Lactuca virosa
Taste
Bitter
Medicinal properties
Potential anti-inflammatory and cytotoxic effects
Anti-inflammatory activity
Studies have shown that 11β,13-dihydrolactucopicrin possesses anti-inflammatory properties
Analgesic activity
Studies have shown that 11β,13-dihydrolactucopicrin possesses analgesic properties
Potential therapeutic applications
Treatment of pain and inflammatory conditions
Cytotoxic effects
Studies have shown that 11β,13-dihydrolactucopicrin has cytotoxic effects on cancer cells
Potential as an anticancer agent
Suggested by its cytotoxic effects on cancer cells
Further research needed
To fully understand the pharmacological effects and potential therapeutic applications of 11β,13-dihydrolactucopicrin.
Check Digit Verification of cas no
The CAS Registry Mumber 125519-47-3 includes 9 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 6 digits, 1,2,5,5,1 and 9 respectively; the second part has 2 digits, 4 and 7 respectively.
Calculate Digit Verification of CAS Registry Number 125519-47:
(8*1)+(7*2)+(6*5)+(5*5)+(4*1)+(3*9)+(2*4)+(1*7)=123
123 % 10 = 3
So 125519-47-3 is a valid CAS Registry Number.
125519-47-3Relevant academic research and scientific papers
Guaianolide Sesquiterpene Lactones from Cichorium intybus (Asteraceae) [1]
Deng, Yonghong,Scott, Lincoln,Swanson, Devin,Snyder, John K.,Sari, Nil,Dogan, Hanzade
, p. 787 - 796 (2007/10/03)
Ten guaianolides, including three previously unreported natural products, were isolated from the aerial parts of Cichorium intybus (Asteraceae), more commonly known as chicory. Two of the new compounds (8 and 9) were analogues of lactupicrin and 11β,13-dihydrolactupicrin, respectively, with the C-15 oxidized to the aldehyde state. The third new natural product, which we have called intybulide A (10), is an isomer of lactucin with the lactone closed to the C-8 oxygen rather than the C-6.