1255237-49-0

Basic information

• Product Name: C₂₀H₂₅NO₂
• Synonyms: C₂₀H₂₅NO₂
• CAS NO: 1255237-49-0
• Molecular Weight: 311.424
• Mol File: 1255237-49-0.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₀H₂₅NO₂(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₀H₂₅NO₂(1255237-49-0)
• EPA Substance Registry System: C₂₀H₂₅NO₂(1255237-49-0)

Safety Data

• Hazardous Substances Data: 1255237-49-0(Hazardous Substances Data)

Upstream product

• 1202778-97-9 cyano-di(4-methyl-benzyl)acetic acid methyl ester 

Downstream Products

• 1202779-10-9 C₂₅H₃₃NO₄ 

Relevant articles and documents

Antimicrobial activity of small β-peptidomimetics based on the pharmacophore model of short cationic antimicrobial peptides

We have synthesized a series of small β-peptidomimetics (Mw 2,2-amino acid coupled to a C-terminal L-arginine amide residue. By varying the lipophilic side-chains of the β2,2-amino acids, we obtained a series of highly potent β-peptidomimetics with high enzymatic stability against α-chymotrypsin and a general low toxicity against human erythrocytes. The most potent β-peptidomimetics displayed minimal inhibitory concentrations of 2.1-7.2 μM against Staphylococcus aureus, methicillin resistant Staphylococcus aureus (MRSA), methicillin resistant Staphylococcus epidermidis (MRSE), and Escherichia coli. Small amphipathic β-peptidomimetics may be a promising class of antimicrobial agents by means of having a similar range of potency and selectivity as larger cationic antimicrobial peptides in addition to improved enzymatic stability and lower costs of production.