125533-82-6

Basic information

• Product Name: Oxazole, 2-bromo- (9CI)
• Synonyms: Oxazole, 2-bromo- (9CI);2-BROMOOXAZOLE;2-broMo-1,3-oxazole;2-broMooxazole,C3H2BrNO;2-Bromooxazole hydrochloride;Oxazole, 2-bromo-
• CAS NO: 125533-82-6
• Molecular Formula: C₃H₂BrNO
• Molecular Weight: 147.95808
• Product Categories: HALIDE;Heterocycles;Intermediates
• Mol File: 125533-82-6.mol
• Article Data: 2

Chemical Properties

• Boiling Point: 166.198 °C at 760 mmHg
• Flash Point: 54.315 °C
• Appearance: Brown to grey crystalline powder
• Density: 1.812 g/cm³
• PKA: -0.58±0.10(Predicted)
• CAS DataBase Reference: Oxazole, 2-bromo- (9CI)(CAS DataBase Reference)
• NIST Chemistry Reference: Oxazole, 2-bromo- (9CI)(125533-82-6)
• EPA Substance Registry System: Oxazole, 2-bromo- (9CI)(125533-82-6)

Safety Data

• Hazardous Substances Data: 125533-82-6(Hazardous Substances Data)

Usage

Uses

2-Bromooxazole is used in the synthesis of 3-[1-(2-Benzoxazolyl)hydrazino]propanenitrile derivatives as inhibitors of immune complex induced inflammation.

Upstream product

• 156780-51-7 2-triethylstannyloxazole 

Downstream Products

• 174150-58-4 oxazol-2-yl-(phenyl)methanone 
• 545424-39-3 4-(1,3-oxazol-2-yl)benzaldehyde 

Relevant articles and documents

Heterocyclic indole derivatives and mono- or diazaindole derivatives

There is provided a compound represented by the general formula (1): wherein Het represents an optionally substituted heterocyclic group; A1and A2each independently represent —CH═, etc.; A3represents —CH2—, etc.; R1represents a 4-fluorophenyl group, etc.; R2represents an alkyl group; n represents 0, 1 or 2, provided that when A1and A2both are —CH═, A3represents —CH2— or —SO2—, which is an indole derivative or a mono- or diazaindole derivative that has COX-2 inhibitory activity and is useful as a pharmaceutical, such as an anti-inflammatory agent, or addition salts thereof with a pharmaceutically acceptable acid or base, or hydrates thereof.