1255528-22-3

Basic information

• Product Name: N-((1-methyl-1H-indol-3-yl)methylene)-1,1-diphenylmethanamine
• Synonyms: N-((1-methyl-1H-indol-3-yl)methylene)-1,1-diphenylmethanamine
• CAS NO: 1255528-22-3
• Molecular Weight: 324.425
• Mol File: 1255528-22-3.mol
• Article Data: 3

Chemical Properties

• CAS DataBase Reference: N-((1-methyl-1H-indol-3-yl)methylene)-1,1-diphenylmethanamine(CAS DataBase Reference)
• NIST Chemistry Reference: N-((1-methyl-1H-indol-3-yl)methylene)-1,1-diphenylmethanamine(1255528-22-3)
• EPA Substance Registry System: N-((1-methyl-1H-indol-3-yl)methylene)-1,1-diphenylmethanamine(1255528-22-3)

Safety Data

• Hazardous Substances Data: 1255528-22-3(Hazardous Substances Data)

Upstream product

• 19012-03-4 N-methyl-3-formylindole 
• 91-00-9 Benzhydrylamine 

Relevant articles and documents

Antimicrobial, crown gall tumor inhibitory and cytotoxicity assays of N-[(1-methyl-1H-indole-3-yl)methylene]amines synthesized by an improved protocol

The present paper reports an easy preparation of imines of N-methyl-1H-indole-3-carboxaldehyde by its condensation with alkyl and aromatic amines in ethanol without using any catalyst or dehydrating agent. The compounds have been screened for their antibacterial, antifungal, crown gall tumor inhibitory, and cytotoxic activities. As a major finding some of the compounds exhibited potential biological activity. The imine containing a 4-chlorophenyl group exhibits potential antitumor activity and brine shrimp lethality against crown gall tumor and brine shrimps, respectively. Furthermore, this imine containing a 4-chlorophenyl group also exhibits significant antifungal activity against Candida albicans fungal strains. The compound containing N-diphenylmethyl group has been observed most active against the Gram-positive bacteria.

A remarkable titanium-catalyzed asymmetric strecker reaction using hydrogen cyanide at room temperature

Close to perfect enantioselectivity (up to 98% ee) is obtained for the formation of amino nitrites using hydrogen cyanide (HCN) as the cyanide source at room temperature for the first time. In an operationally simple process, the catalyst generated from a partially hydrolyzed titanium alkoxide (PHTA) and (S)-N-salicyl-ss-amino alcohol ligand, catalyzes the cyanation of imines in a short reaction time.