1255528-46-1Relevant articles and documents
Efficient C2 functionalisation of 2H-2-imidazolines
Bon, Robin S.,Sprenkels, Nanda E.,Koningstein, Manoe M.,Schmitz, Rob F.,De Kanter, Frans J. J.,Doemling, Alexander,Groen, Marinus B.,Orru, Romano V. A.
, p. 130 - 137 (2008)
Alkylation and oxidation of 2H-2-imidazolines, followed by regioselective deprotection, thionation and microwave-assisted Liebeskind-Srogl reaction, efficiently led to 2-aryl-2-imidazolines as new analogues of p53-hdm2 interaction inhibitors (Nutlins). Th