1255529-34-0

Basic information

• Product Name: Edoxaban iMpurities
• Synonyms: Edoxaban iMpurities;Edoxaban Impurity;Edoxaban Impurity 1;Edoxaban Impurity 10;Edoxaban Impurity 11;Edoxaban Impurity 12;Edoxaban Impurity 13;Edoxaban Impurity 16 Oxalate
• CAS NO: 1255529-34-0
• Molecular Formula: C₁₆H₂₂ClN₅O₃
• Molecular Weight: 285.38
• EINECS: -0
• Mol File: 1255529-34-0.mol
• Article Data: 1

Chemical Properties

• Boiling Point: 434.4±45.0 °C(Predicted)
• Appearance: /
• Density: 1.09±0.1 g/cm3(Predicted)
• PKA: 11.96±0.60(Predicted)
• CAS DataBase Reference: Edoxaban iMpurities(CAS DataBase Reference)
• NIST Chemistry Reference: Edoxaban iMpurities(1255529-34-0)
• EPA Substance Registry System: Edoxaban iMpurities(1255529-34-0)

Safety Data

• Hazardous Substances Data: 1255529-34-0(Hazardous Substances Data)

Upstream product

• 1255529-33-9 (1S,2R,5R)-2-({2-[(5-chloropyridin-2-yl)amino]-2-oxoacetyl}amino)-5-[(dimethylamino)carbonyl]cyclohexylcarbamic acid tert-butyl ester 

Relevant articles and documents

OXAMIDE DERIVATIVE

The present invention provides an isomer of N1-(5-chloropyridin-2-yl)-N2-((1S,2R,4S)-4-[(dimethylamino)carbonyl]-2-{[(5-methyl-4,5,6,7-tetrahydrothiazolo[5,4-c]pyridin-2-yl)carbonyl]amino}cyclohexyl)ethanediamide represented by formula (II) or a salt thereof, or a solvate thereof. Such an isomer or a salt thereof, or a solvate thereof is useful as a standard in a test for inspecting impurities in a pharmaceutical composition containing a compound represented by formula (II) or a salt thereof, or a hydrate thereof. The present invention also relates to a substantially pure compound that is useful as a preventive and/or therapeutic drug for thrombotic diseases, and a pharmaceutical composition containing the substantially pure compound.