125563-02-2Relevant academic research and scientific papers
CARBON-ACYLATIONS IN THE PRESENCE OF MAGNESIUM OXIDE. A SIMPLE SYNTHESIS OF METHANETRICARBOXYLIC ESTERS
Skarzewski, Jacek
, p. 4593 - 4598 (2007/10/02)
Magnesium oxide is an effective reagent for the carbon-acylation of malonates with either acyl chlorides or chloroformates.Various malonic esters (methyl, ethyl, isopropyl and isobutyl) were easily alkoxycarbonylated to give the corresponding methanetricarboxylic esters.The reaction scope and limitations have been elaborated.
