1255646-17-3Relevant academic research and scientific papers
An efficient synthesis of 6-nitro-and 6-amino-3H-imidazo[4,5-b ]pyridines by cyclocondensation of 1-substituted 1H-imidazol-5-amines with 3-nitro-4H-chromen-4-one
Ostrovskyi, Dmytro,Iaroshenko, Viktor O.,Petrosyan, Andranik,Dudkin, Sergii,Ali, Iftikhar,Villinger, Alexander,Tolmachev, Andrei,Langer, Peter
experimental part, p. 2299 - 2303 (2010/11/03)
The reaction of 3-nitro-4H-chromen-4-one with in situ generated 1-substituted 5-amino-1H-imidazoles affords a set of 1-substituted 6-nitro-3H-imidazo[4,5-b]pyridines which represent potential adenosine deaminase (ADA) inhibitors. Reduction of the nitro group results in the formation of the corresponding 6-amino-3H-imidazo[4,5-b]pyridines. Georg Thieme Verlag Stuttgart - New York.
