1255646-83-3Relevant academic research and scientific papers
Total synthesis of (+)-roxaticin via C-C bond forming transfer hydrogenation: A departure from stoichiometric chiral reagents, auxiliaries, and premetalated nucleophiles in polyketide construction
Han, Soo Bong,Hassan, Abbas,Kim, In Su,Krische, Michael J.
supporting information; experimental part, p. 15559 - 15561 (2011/01/03)
A total synthesis of the oxo-polyene macrolide (+)-roxaticin is achieved in 20 steps from 1,3-propanediol. In this approach, 9 of 10 C-C bonds formed in the longest linear sequence are made via metal catalysis, including 7 C-C bonds formed by iridium cata
