1255649-50-3Relevant articles and documents
Regioselective deuteration of alcohols in D2O catalysed by homogeneous manganese and iron pincer complexes
Kar, Sayan,Goeppert, Alain,Sen, Raktim,Kothandaraman, Jotheeswari,Surya Prakash
supporting information, p. 2706 - 2710 (2018/07/05)
We report a convenient and cost-effective protocol for the regioselective deuteration of primary and secondary alcohols using Earth abundant homogeneous first row transition metal pincer catalysts. D2O is utilized as both a deuterium source and a solvent, allowing for a benign inexpensive process. Depending on the metal selected (Mn or Fe), a high degree of deuterium incorporation was observed selectively either at the α and β position (Mn) or exclusively at the α position (Fe), for primary alcohols. This simple, efficient, and cost-effective protocol for alcohol C-H bond deuteration constitutes a powerful tool for the large scale synthesis of deuterated molecules.
Kinetic studies of vapor-phase hydrogenolysis of butyl butyrate to butanol over Cu/ZnO/Al2O3 catalyst
Ju, In Bum,Jeon, Wonjin,Park, Myung-June,Suh, Young-Woong,Suh, Dong Jin,Lee, Chang-Ha
experimental part, p. 100 - 106 (2011/06/17)
Kinetic investigations on the hydrogenolysis of butyl butyrate to butanol over a commercial Cu/ZnO/Al2O3 catalyst were conducted. The catalytic measurements at atmospheric pressure showed that the rate of hydrogenolysis was approximately 0.67 order with respect to butyl butyrate and had a positive effect for hydrogen. The activation energy of this reaction was measured to be about 62 kJ/mol, and D2 isotope studies corroborated that the hydrogenolysis of butyl butyrate proceeds via dissociative adsorption of ester producing C3H7CO and C4H9O fragments. In addition, kinetic studies, interpreted by applying the basis of the Langmuir-Hinshelwood model, suggested that the rate-determining step involves the dissociative adsorption of butyl butyrate. Finally, the rate expression derived in this study provided precise and reasonable fitting results, and an activation energy close to the value obtained from the power law equation.