1255652-00-6Relevant articles and documents
Enantiodifferentiating endo-selective oxylactonization of ortho-alk-l-enylbenzoate with a lactate-derived aryl-λ3-iodane
Fujita, Morifumi,Yoshida, Yasushi,Miyata, Kazuyuki,Wakisaka, Akihiro,Sugimura, Takashi
, p. 7068 - 7071 (2010)
It's the hype: The asymmetric synthesis of 3-alkyl-4-oxyisochroman-1-one is achieved by oxylactonization of ortho-alk-1-enylbenzoate with a series of optically active hypervalent iodine(III) reagents prepared from lactate or valine as a chiral source (see scheme). The oxylactonization is highly regio-, diastereo-, and enantioselective. 2010 Wiley-VCH Verlag GmbH & Co. KGaA.