1255666-28-4

Basic information

• Product Name: 1-tert-butyl 2-Methyl 4,4-difluoropiperidine-1,2-dicarboxylate
• Synonyms: 1-tert-butyl 2-Methyl 4,4-difluoropiperidine-1,2-dicarboxylate
• CAS NO: 1255666-28-4
• Molecular Formula: C₁₂H₁₉F₂NO₄
• Molecular Weight: 279.2803664
• Mol File: 1255666-28-4.mol
• Article Data: 3

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 1-tert-butyl 2-Methyl 4,4-difluoropiperidine-1,2-dicarboxylate(CAS DataBase Reference)
• NIST Chemistry Reference: 1-tert-butyl 2-Methyl 4,4-difluoropiperidine-1,2-dicarboxylate(1255666-28-4)
• EPA Substance Registry System: 1-tert-butyl 2-Methyl 4,4-difluoropiperidine-1,2-dicarboxylate(1255666-28-4)

Safety Data

• Hazardous Substances Data: 1255666-28-4(Hazardous Substances Data)

Usage

The compound features three different substituents

a tert-butyl group (C4H9), a methyl group (CH3), and a difluoro group (F2), which contribute to its unique chemical properties and reactivity.
4. Building block in pharmaceutical synthesis
The compound is often used as a starting material or intermediate in the synthesis of various pharmaceutical drugs, particularly those targeting the central nervous system.
5. Key intermediate in agrochemical production
The compound serves as an important intermediate in the production of various agrochemicals, such as pesticides and herbicides.
6. Unique chemical properties and reactivity
The presence of the tert-butyl and difluoro groups in the compound's structure imparts unique chemical properties and reactivity, making it valuable in the development of novel chemical compounds for a variety of applications.

Upstream product

• 144913-66-6 4-hydroxy-2-piperidine carboxylic acid methyl ester 
• 847029-99-6 1-benzyl 2-methyl 4-hydroxypiperidine-1,2-dicarboxylate 
• 125104-19-0 (±)-methyl 1-benzyloxycarbonyl-4-oxopiperidine-2-carboxylate 
• 24424-99-5 di-tert-butyl dicarbonate 
• 1259011-96-5 (±)-methyl 1-benzyloxycarbonyl-4,4-difluoropiperidine-2-carboxylate 

Downstream Products

• 1259011-99-8 (±) tert-butyl 2-(aminomethyl)-4,4-difluoropiperidine-1-carboxylate 
• 1259012-00-4 tert-butyl 2-((2-(5-chloro-1-tosyl-1H-pyrrolo[2,3-b]pyridin-3-yl)-5-fluoropyrimidin-4-ylamino)methyl)-4,4-difluoropiperidine-1-carboxylate 

Relevant articles and documents

Inhibitors of influenza viruses replication

Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.

INHIBITORS OF INFLUENZA VIRUSES REPLICATION

Methods of inhibiting the replication of influenza viruses in a biological sample or patient, of reducing the amount of influenza viruses in a biological sample or patient, and of treating influenza in a patient, comprises administering to said biological sample or patient an effective amount of a compound represented by Structural Formula (I): or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A compound is represented by Structural Formula (IA) or a pharmaceutically acceptable salt thereof, wherein the values of Structural Formula (IA) are as described herein. A pharmaceutical composition comprises an effective amount of such a compound or pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier, adjuvant or vehicle.