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1255708-36-1

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1255708-36-1 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 1255708-36-1 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,5,7,0 and 8 respectively; the second part has 2 digits, 3 and 6 respectively.
Calculate Digit Verification of CAS Registry Number 1255708-36:
(9*1)+(8*2)+(7*5)+(6*5)+(5*7)+(4*0)+(3*8)+(2*3)+(1*6)=161
161 % 10 = 1
So 1255708-36-1 is a valid CAS Registry Number.

1255708-36-1Downstream Products

1255708-36-1Relevant articles and documents

Indazolylpyrazolopyrimidine as highly potent B-Raf inhibitors with in vivo activity

Wang, Xiaolun,Berger, Dan M.,Salaski, Edward J.,Torres, Nancy,Dutia, Minu,Hanna, Cilien,Hu, Yongbo,Levin, Jeremy I.,Powell, Dennis,Wojciechowicz, Donald,Collins, Karen,Frommer, Eileen,Lucas, Judy

supporting information; scheme or table, p. 7874 - 7878 (2011/01/12)

Novel indazolylpyrazolo[1,5-a]pyrimidine analogues have been prepared and found to be extremely potent type I B-Raf inhibitors. The lead compound shows good selectivity against a panel of 60 kinases, possesses a desirable pharmacokinetic profile, and demonstrates excellent in vivo antitumor efficacy in B-Raf mutant xenograft models.

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