1255922-72-5Relevant academic research and scientific papers
A facile method for synthesis of polysubstituted naphthalene derivatives through pyrrolidine catalyzed domino reaction
Li, Shi-Guang,Hu, Xiu-Qin,Jia, Zhen-Xin,Xu, Peng-Fei
supporting information; experimental part, p. 8557 - 8561 (2010/11/05)
A novel synthetic method for polysubstituted naphthalene derivatives via a pyrrolidine-mediated cascade Michael/Henry reaction was developed, in which easily prepared 2-(2-oxoethyl)benzaldehydes and nitroalkenes were employed as the starting materials. The reaction consists of four consecutive reactions that include a cascade Michael/Henry reaction, a dehydration reaction, and an aromatization reaction in one pot to afford synthetically important naphthalene derivatives with moderate yields.
