1256155-48-2Relevant academic research and scientific papers
Asymmetrie synthesis of fluorinated flavanone derivatives by an organocatalytic tandem intramolecular oxa-michael Addition/electrophilic fluorination reaction by using bifunctional cinchona alkaloids
Wang, Hai-Feng,Cui, Hai-Feng,Chai, Zhuo,Li, Peng,Zheng, Chang-Wu,Yang, Ying-Quan,Zhao, Gang
supporting information; experimental part, p. 13299-13303+13273 (2010/06/17)
"Chemical Equation Presented" A bifunetional quinidine derivative, containing a trifluoromethyl group, was found to catalyze a tandem intramolecular oxa-Michael addition/electrophilic fluorination reaction of acti-vated α,β-unsaturated ketones (see scheme). A series of chiral fluorinated flavanone derivatives were obtained in excellent yields and with high enantioselectivities.
