1256269-48-3Relevant academic research and scientific papers
A κ opioid pharmacophore becomes a spinally selective κ-δ Agonist when modified with a basic extender arm
Tang, Ye,Yang, Jie,Lunzer, Mary M.,Powers, Michael D.,Portoghese, Philip S.
supporting information; experimental part, p. 7 - 10 (2011/04/17)
We have explored the concept of a molecular extender arm attached to a κ opioid agonist pharmacophore 3 (ICI-199,441) in an effort to potentially interact with a complementary group on a neighboring opioid receptor. The molecular arm containing a terminal
