1256282-70-8Relevant academic research and scientific papers
A new non-cross-linked polystyrene supported 2-phenylimino-2-oxazolidine chiral auxiliary: Synthesis and application in asymmetric alkylation reactions
Hu, Fu-Qiang,Xia, De-Xin,Lu, Cui-Fen,Chen, Zu-Xing,Yang, Gui-Chun
, p. 5552 - 5554 (2010)
The synthesis of novel non-cross-linked polystyrene supported 2-phenylimino-2-oxazolidine is described, and its use as a chiral auxiliary in asymmetric alkylation reactions is demonstrated by the synthesis of several chiral amides (>96%ee). Furthermore, recovery and recycling of the polymer-supported chiral auxiliary were successfully achieved without appreciable reduction in the yield or stereoselectivity. The synthesis of novel non-cross-linked polystyrene supported 2-phenylimino-2-oxazolidine is described, and its use as a chiral auxiliary in asymmetric alkylation reactions is demonstrated by the synthesisof several chiral amides (>96%ee). Recovery and recycling of the polymer-supported chiral auxiliary were successfully achieved without appreciable reduction in the yield or stereoselectivity.
