1256346-60-7Relevant academic research and scientific papers
Design, synthesis, and structure-activity relationships of 3-ethynyl-1 H-indazoles as inhibitors of the phosphatidylinositol 3-kinase signaling pathway
Barile, Elisa,De, Surya K.,Carlson, Coby B.,Chen, Vida,Knutzen, Christine,Riel-Mehan, Megan,Yang, Li,Dahl, Russell,Chiang, Gary,Pellecchia, Maurizio
experimental part, p. 8368 - 8375 (2011/02/23)
A new series of 3-ethynyl-1H-indazoles has been synthesized and evaluated in both biochemical and cell-based assays as potential kinase inhibitors. Interestingly, a selected group of compounds identified from this series exhibited low micromolar inhibitio
