1256359-01-9 Usage
Chemical compound
Boronic ester with a bulky substituent
Use
Organic synthesis and pharmaceutical research
Reactivity
Useful for Suzuki-Miyaura cross-coupling reactions and organic transformations
Stability
Stable compound
Solubility
Good solubility in common organic solvents
Applications
Versatile reagent for synthetic chemistry, valuable tool for complex molecule construction, and development of new drug candidates
Interest
Pharmaceutical industry for synthesis of biologically active compounds in medicinal chemistry
Check Digit Verification of cas no
The CAS Registry Mumber 1256359-01-9 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,3,5 and 9 respectively; the second part has 2 digits, 0 and 1 respectively.
Calculate Digit Verification of CAS Registry Number 1256359-01:
(9*1)+(8*2)+(7*5)+(6*6)+(5*3)+(4*5)+(3*9)+(2*0)+(1*1)=159
159 % 10 = 9
So 1256359-01-9 is a valid CAS Registry Number.
1256359-01-9Relevant academic research and scientific papers
BET INHIBITORS FOR MODULATING DUX4 EXPRESSION IN FSHD
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, (2020/07/14)
The present disclosure provides BET inhibitors of the formula: wherein the variables are defined herein, as well as pharmaceutical compositions thereof. The present disclosure also provides methods of treating a patient comprising administering a bromo- and extra-terminal (BET) domain inhibitor for the treatment of FSHD which modulates DUX4 expression. In some embodiments, the present methods comprise using one or more BET inhibitors as a therapeutic agent for the treatment of FSHD patients including patients who are being treated with one or more palliative treatments such as therapy and/or agents which lead to increased muscle mass.
