1256362-63-6

Basic information

• Product Name: (28S)-3-O-acetyl-28-(phenylethynyl)-lup-20⁽²⁹⁾-en-3,28-diol
• Synonyms: (28S)-3-O-acetyl-28-(phenylethynyl)-lup-20⁽²⁹⁾-en-3,28-diol
• CAS NO: 1256362-63-6
• Molecular Weight: 584.883
• Mol File: 1256362-63-6.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: (28S)-3-O-acetyl-28-(phenylethynyl)-lup-20⁽²⁹⁾-en-3,28-diol(CAS DataBase Reference)
• NIST Chemistry Reference: (28S)-3-O-acetyl-28-(phenylethynyl)-lup-20⁽²⁹⁾-en-3,28-diol(1256362-63-6)
• EPA Substance Registry System: (28S)-3-O-acetyl-28-(phenylethynyl)-lup-20⁽²⁹⁾-en-3,28-diol(1256362-63-6)

Safety Data

• Hazardous Substances Data: 1256362-63-6(Hazardous Substances Data)

Upstream product

• 27570-21-4 3-O-acetylbetulinal 
• 536-74-3 phenylacetylene 

Relevant articles and documents

Synthesis, cytotoxicity and liposome preparation of 28-acetylenic betulin derivatives

Several novel betulin derivatives were prepared and evaluated for their antitumor activity. 3-O-Acetylbetulinic aldehyde served as an ideal starting material for the synthesis of 28-acetylenic derivatives. These compounds were further transformed into pyrazoles and 1,2,3-triazoles. Also, the synthesis of 3-amino substituted butenolides was carried out. The compounds were screened for their antitumor activity in a panel of 15 human cancer cell lines in a sulforhodamine B (SRB) assay. Several compounds showed a noteworthy antitumor activity. In addition, the possibility of encapsulation into liposomes was examined, thereby resulting in an increased cytotoxicity. The results from a trypan-blue test and from DNA laddering provided evidence for an apoptotic cell death.