1256379-85-7Relevant academic research and scientific papers
Transfer of Sequence Information and Replication of Diimine Duplexes
Strom, Kyle R.,Szostak, Jack W.,Prywes, Noam
, p. 3754 - 3761 (2019)
The ability of the biopolymers RNA and DNA to store and transfer information is essential to life. Herein, we demonstrate template-directed replication in a set of dimer duplexes that use reversible covalent bonds to form base-pairing interactions. Binary sequence information was encoded as a sequence of aniline and benzaldehyde subunits linked together by a diethynyl benzene backbone. These dimers formed sequence-specific, imine-linked duplexes, which could be separated and used as templates for the synthesis of daughter duplexes with identical sequences.
Double-decked molecular crescents
Lin, Li,Zhang, Jiaxin,Wu, Xiangxiang,Liang, Guoxing,He, Lan,Gong, Bing
supporting information; experimental part, p. 7361 - 7363 (2010/12/19)
Molecules with a defined crescent shape have been generated from the folding or covalent locking of curved structural components connected together via multiple covalent tethers.
