125640-81-5

Basic information

• Product Name: 4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide
• Synonyms: 4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide
• CAS NO: 125640-81-5
• Molecular Weight: 311.404
• Mol File: 125640-81-5.mol
• Article Data: 11

Chemical Properties

• CAS DataBase Reference: 4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide(CAS DataBase Reference)
• NIST Chemistry Reference: 4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide(125640-81-5)
• EPA Substance Registry System: 4-methyl-N-(naphthalene-2-ylmethyl)benzenesulfonamide(125640-81-5)

Safety Data

• Hazardous Substances Data: 125640-81-5(Hazardous Substances Data)

Upstream product

• 70-55-3 toluene-4-sulfonamide 
• 66-99-9 β-naphthaldehyde 
• 1592-38-7 2-Naphthalenemethanol 
• 17692-84-1 2-naphthyl N-tosyl imine 
• 613-46-7 2-naphthalenecarbonitrile 
• 195515-75-4 S-(2-Pyridyl)-S-(2-naphthylmethyl)-N-p-tosylsulfimide 
• 4104-47-6 N-sulfinyl-p-toluenesulfonamide 
• 2018-90-8 naphthalen-2-ylmethylamine 
• 98-59-9 p-toluenesulfonyl chloride 

Downstream Products

• 1186132-33-1 3-tosyl-1-vinyl-1,2,3,4-tetrahydrobenzo[f]isoquinoline 
• 1186132-32-0 (Z)-N-(4-hydroxybut-2-en-1-yl)-4-methyl-N-(naphthalen-2-ylmethyl)benzenesulfonamide 
• 1186132-48-8 C₂₈H₃₇NO₃SSi 

Relevant articles and documents

Copper-boryl mediated transfer hydrogenation of N-sulfonyl imines using methanol as the hydrogen donor

B2Pin2-assisted copper-catalyzed transfer hydrogenation of aromatic sulfonylimines has been achieved, delivering a variety of aryl/heteroaryl sulfonamides in good to excellent yields under mild reaction conditions and with methanol a

A bifunctional strategy for N-heterocyclic carbene-stabilized iridium complex-catalyzed: N -alkylation of amines with alcohols in aqueous media

Through the strategy of combining bifunctional 2-hydroxypyridine and a thermally stable N-heterocyclic carbene ligand, an Ir-catalyzed N-monoalkylation reaction has been developed in aqueous media under base-free conditions. This reaction proceeds smoothly with high yields of various aromatic amines and sulfonamides with a wide range of primary alcohols. Experimental and computational studies revealed a metal-ligand cooperative mechanism and its thermal stability during the bifunctional catalysis in aqueous media.

The N-alkylation of sulfonamides with alcohols in water catalyzed by the water-soluble iridium complex {Cp*[6,6'-(OH)2bpy](H 2O)}[OTf]2

The water-soluble iridium complex {Cp*[6,6'-(OH)2bpy] (H2O)}[OTf]2 (Cp=ν5-pentamethylcyclopentadienyl, bpy=2,2'-bipyridine) was found to be a general and highly efficient catalyst for the Nalkylation of the poor nucleophilic sulfonamides with alcohols as alkylating agents in water. The presence of OH units in the bpy ligand is crucially important for the catalytic activity of the iridium complex. Mechanistic investigations revealed that the catalytically active species is a ligand-metal bifunctional iridium complex bearing an N,N'-chelated 2,2'-bipyridinated ligand and an aqua ligand. Notably, the present catalytic system and the proposed mechanism provide a new horizon and scope for the development of "hydrogen autotransfer (or hydrogen-borrowing) processes".