125641-60-3

Basic information

• Product Name: 3-tert-butylpyridin-2(1H)-one
• Synonyms: 3-tert-butylpyridin-2(1H)-one
• CAS NO: 125641-60-3
• Molecular Formula: C9H13NO
• Molecular Weight: 151.20562
• Mol File: 125641-60-3.mol
• Article Data: 2

Chemical Properties

• Appearance: /
• CAS DataBase Reference: 3-tert-butylpyridin-2(1H)-one(CAS DataBase Reference)
• NIST Chemistry Reference: 3-tert-butylpyridin-2(1H)-one(125641-60-3)
• EPA Substance Registry System: 3-tert-butylpyridin-2(1H)-one(125641-60-3)

Safety Data

• Hazardous Substances Data: 125641-60-3(Hazardous Substances Data)

Upstream product

• 1070-83-3 tert-Butylacetic acid 
• 61066-88-4 benzyl 3,3-dimethylbutanoate 
• 917-92-0 3,3-Dimethylbut-1-yne 
• 125641-54-5 1,3-Di-tert-butyl-1H-pyridin-2-one 

Relevant articles and documents

Formation of α-SF5-enolate enables preparation of 3-SF5-quinolin-2-ones, 3-SF5-Quinolines, and 3-SF5-pyridin-2-ones: Evaluation of their physicochemical properties

This study describes, for the first time, the generation of a SF5-substituted ester enolate from benzyl SF5-acetate under soft enolization conditions, which in turn participates in aldol addition reactions in high yield. The reaction was applied in the synthesis of 3-SF5-quinolin-2-ones, 3-SF5-quinolines, and 3-SF5-pyridin-2-ones, none of which have previously been reported. To provide guidelines for their use in drug discovery, the physicochemical properties of these building blocks were determined and compared with those of their CF3- and t-Bu-analogues.