1256482-82-2 Usage
General Description
2-Bromo-3,6-difluorophenylacetonitrile, 96% is a chemical compound with a high level of purity, consisting of a 2-bromo-3,6-difluorophenyl group attached to an acetonitrile functional group. 2-BroMo-3,6-difluorophenylacetonitrile, 96% is commonly used as an intermediate in the synthesis of various pharmaceuticals, agrochemicals, and specialty chemicals. Its high purity level makes it suitable for use in research and manufacturing processes where precise and consistent results are required. It is important to handle and store this compound with care, as it may pose health and environmental hazards if not managed properly.
Check Digit Verification of cas no
The CAS Registry Mumber 1256482-82-2 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,6,4,8 and 2 respectively; the second part has 2 digits, 8 and 2 respectively.
Calculate Digit Verification of CAS Registry Number 1256482-82:
(9*1)+(8*2)+(7*5)+(6*6)+(5*4)+(4*8)+(3*2)+(2*8)+(1*2)=172
172 % 10 = 2
So 1256482-82-2 is a valid CAS Registry Number.
1256482-82-2Relevant articles and documents
Phenethyl nicotinamides, a novel class of NaV1.7 channel blockers: Structure and activity relationship
Kers, Inger,MacSari, Istvan,Csjernyik, Gabor,Nyloef, Martin,Skogholm, Karin,Sandberg, Lars,Minidis, Alexander,Bueters, Tjerk,Malmborg, Jonas,Eriksson, Anders B.,Lund, Per-Eric,Venyike, Elisabet,Luo, Lei,Nystroem, Jan-Erik,Besidski, Yevgeni
, p. 6108 - 6115 (2012/10/30)
The NaV1.7 ion channel is an attractive target for development of potential analgesic drugs based on strong genetic links between mutations in the gene coding for the channel protein and inheritable pain conditions. The (S)-N-chroman-3-ylcarboxamide series, exemplified by 1, was used as a starting point for development of new channel blockers, resulting in the phenethyl nicotinamide series. The structure and activity relationship for this series was established and the metabolic issues of early analogues were addressed by appropriate substitutions. Compound 33 displayed acceptable overall in vitro properties and in vivo rat PK profile.
