1256554-07-0

Basic information

• Product Name: (R)-1-(3-fluorophenyl)-2-nitroethanol
• Synonyms: (R)-1-(3-fluorophenyl)-2-nitroethanol
• CAS NO: 1256554-07-0
• Molecular Weight: 185.155
• Mol File: 1256554-07-0.mol

Chemical Properties

• CAS DataBase Reference: (R)-1-(3-fluorophenyl)-2-nitroethanol(CAS DataBase Reference)
• NIST Chemistry Reference: (R)-1-(3-fluorophenyl)-2-nitroethanol(1256554-07-0)
• EPA Substance Registry System: (R)-1-(3-fluorophenyl)-2-nitroethanol(1256554-07-0)

Safety Data

• Hazardous Substances Data: 1256554-07-0(Hazardous Substances Data)

Upstream product

• 75-52-5 nitromethane 
• 456-48-4 3-Fluorobenzaldehyde 

Relevant articles and documents

Biphenyl-Based Bis(thiourea) Organocatalyst for Asymmetric and syn -Selective Henry Reaction

A scalable, efficient and chromatography-free synthesis of a new enantiopure C 2-symmetric bis(thiourea) catalyst was accomplished from a readily available starting material. The developed strategy could be conducted on a multi-gram scale. Both the prepared enantiomers of the bis(thiourea) organocatalyst have been tested in the asymmetric Henry reaction under thoroughly optimized conditions during which an unusual solvent effect on enantioselectivity was found. The corresponding adducts were obtained in excellent yields with good to excellent enantioselectivities. The achieved high reactivity and enantioselectivity in the nitroaldol reaction of nitroalkanes with aromatic aldehydes suggests promising potential for this catalyst. Moreover, a significant syn-diastereoselectivity was observed.

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Immobilized catalysts have attracted chemists’ attention for long time because of convenient recycling, which is very important for some special catalyst even immobilizations accompanying the decrease of catalytic activity and selectivity. Our group focus

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Copper-bearing chirality helical coordination polymer and preparation method and application thereof

The invention discloses a copper-bearing chirality helical coordination polymer and a preparation method and application thereof. The chemical formula is {[Cu (R,R-cdpa) (H2O)2].2NO3. 2H2O}. The preparation method comprises the steps of adding 5 mL of methanol solution into copper dinitrate-water(1/3) and R,R-cdpa to be mixed to obtain suspension liquid and enabling the suspension liquid to stand at room temperature to obtain the copper-bearing chirality helical coordination polymer. The copper-bearing chirality helical coordination polymer has the advantages that a double chelate ligand R,R-cdpa based on chiraity cyclohexanediamine and Cu (II) are utilized to prepare a one-dimensional helical coordination polymer, and the coordination polymer has a right hand 31 helical structure and has second-order non-linear optical activity. The preparing technology is simple, a complex synthesis device is not needed, the production cost is reduced, and the prepared coordination polymer can be applied to asymmetric Henry reaction of aromatic aldehyde and nitromethane.

A right hand spiral coordination polymer and its preparation method and application (by machine translation)

The invention discloses a right-hand spiral coordination polymer and its preparation method and application, its chemical formula is {[ cu (R, R-cdea) (H 2 O)]. 2NO 3. 2H 2 O} n, the preparation method includes the cu (NO 3) 2 · 3H 2 O and R, R-cdea by adding 5 ml of methanol solution, prepared by suspension, the suspension after standing at room temperature, that is, right hand spiral coordination polymer prepared. For the advantages of: the invention is based on the double of the diamine chiral link oneself chelating ligand R, with R-cdea cu (II) construct the one-dimensional spiral coordination polymer, with the same right hand 3 1 spiral structure, and with second-order non-linear optical activity; at the same time, simple preparation process of the present invention, does not need complex synthesis apparatus, reduce the production cost; in addition, preparation of the complex polymer can be applied to the aromatic aldehyde with nitromethane asymmetric henly reaction. (by machine translation)

Right-handed 4 helix coordination polymer and its preparation method and use

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Camphor Schiff base, and preparation method and application thereof

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