1256564-27-8Relevant articles and documents
One pot synthesis of substituted [1,2,4]-Triazolo [1',2':1,2]pyrimido [6,5-b]-quinoline and its antibacterial activity
Joshi, Ratnadeep S.,Mandhane, Priyanka G.,Chate, Asha V.,Khan, Wajid,Gill, Charansingh H.
experimental part, p. 2341 - 2344 (2010/11/16)
A convenient synthesis of substituted [1,2,4]-triazolo [1',2':1,2] pyrimido[6,5-b]-quinoline 4(a-i) from substituted 2-chloroquinoline-3- carbaldehyde 1(a-i) and 4H-1,2,4-triazol-3-amine 2 by using SiO 2/K2CO3 under microwave irradiation. This method affords the [1,2,4]-Triazolo [1',2':1,2]pyrimido[6,5-b]-quinoline 4(a-i) under the influence of microwave irradiation in solvent-free conditions within short span (12 - 20 min), & gaves excellent yields (89 -95%). All the synthesized compounds were further screened for their antibacterial activities. Some of our compounds showed excellent antibacterial activities against control drugs.