1256724-01-2Relevant academic research and scientific papers
Synthesis and biological evaluation of apogossypolone derivatives as pan-active inhibitors of antiapoptotic B-cell lymphoma/leukemia-2 (Bcl-2) family proteins
Wei, Jun,Kitada, Shinichi,Stebbins, John L.,Placzek, William,Zhai, Dayong,Wu, Bainan,Rega, Michele F.,Zhang, Ziming,Cellitti, Jason,Yang, Li,Dahl, Russell,Reed, John C.,Pellecchia, Maurizio
, p. 8000 - 8011 (2011/03/19)
Overexpression of antiapoptotic Bcl-2 family proteins is commonly related with tumor maintenance, progression, and chemoresistance. Inhibition of these antiapoptotic proteins is an attractive approach for cancer therapy. Guided by nuclear magnetic resonan
