1256795-49-9Relevant academic research and scientific papers
Total synthesis of bryostatin 16 using a Pd-catalyzed diyne coupling as macrocyclization method and synthesis of C20-epi-bryostatin 7 as a potent anticancer agent
Trost, Barry M.,Dong, Guangbin
supporting information; experimental part, p. 16403 - 16416 (2011/02/23)
Asymmetric total synthesis of bryostatin 16 was achieved in 26 steps in the longest linear sequence and in 39 total steps from aldehyde 10. A Pd-catalyzed alkyne-alkyne coupling was employed for the first time as a macrocyclization method in a natural pro
