1256921-77-3

Basic information

• Product Name: C₂₇H₃₃NO₄
• Synonyms: C₂₇H₃₃NO₄
• CAS NO: 1256921-77-3
• Molecular Weight: 435.563
• Mol File: 1256921-77-3.mol
• Article Data: 1

Chemical Properties

• CAS DataBase Reference: C₂₇H₃₃NO₄(CAS DataBase Reference)
• NIST Chemistry Reference: C₂₇H₃₃NO₄(1256921-77-3)
• EPA Substance Registry System: C₂₇H₃₃NO₄(1256921-77-3)

Safety Data

• Hazardous Substances Data: 1256921-77-3(Hazardous Substances Data)

Upstream product

• 1612-45-9 C₁₉H₂₅NO₄ 
• 122-78-1 phenylacetaldehyde 

Downstream Products

• 3941-92-2 C₂₅H₂₉NO₃ 

Relevant articles and documents

Design and synthesis of KNT-127, a δ-opioid receptor agonist effective by systemic administration

We have reported previously the novel δ-opioid agonist, SN-28, which was more potent in in vitro assays than the prototype δ-agonists, TAN-67 and SNC-80. However, when administered by subcutaneous injection, this compound showed no analgesic effect at dosages greater than 30 mg/kg in the acetic acid writhing test. We speculated that SN-28 was not effective in the test because the presence of the charged ammonium groups prevented its penetration through the blood-brain barrier. On the basis of our proposal, we designed the novel δ-agonist, KNT-127, which was effective with systemic administration.