125706-38-9

Upstream product

• 79295-14-0 methyl 2-((4-methoxyphenyl)thio)acetate 
• 696-63-9 4-Methoxybenzenethiol 
• 2365-48-2 Methyl thioglycolate 

Downstream Products

• 3996-45-0 <(4-Methoxyphenyl)sulfinyl>acetic acid 
• 125706-43-6 (S)-(-)-<(4-Methoxyphenyl)sulfinyl>acetic acid 
• 125761-97-9 (R)-(+)-Methyl <(4-methoxyphenyl)sulfinyl>acetate 

Relevant academic research and scientific papers

Catalyst-free visible-light-initiated oxidative coupling of aryldiazo sulfones with thiols leading to unsymmetrical sulfoxides in air

A facile and efficient visible-light-driven method has been developed to construct sulfoxides via oxidative coupling of aryldiazo sulfones with thiols using the O2 in air as the oxidant. This reaction could be performed at room temperature under catalyst- and additive-free conditions. The present methodology offers a mild and environmentally benign approach to obtain a library of sulfoxides in good yields with favorable functional group tolerance.

Method for preparing visible light promoted asymmetric sulfoxide compound

The invention belongs to the field of organic synthetic chemistry, particularly relates to a preparation method of an asymmetric sulfoxide compound, and particularly discloses a method for synthesizing the asymmetric sulfoxide compound based on visible light catalysis. A compound shown in the formula I and a compound shown in the formula II are added to a reactor, a mixture of an organic solvent and water is added as a reaction solvent, the reactor is connected to air, under the irradiation of visible light, a reaction at a room temperature is performed for 16-40 hours; and after a detection reaction of a TLC thin layer chromatography plate is completed, pure water is added, then the extraction is performed, extract liquid is combined and dried, the extract liquid is concentrated and purified to obtain a compound shown in the formula III, and the compound is the asymmetric sulfoxide compound. The reaction conditions are mild, energy is clean, a strong oxidant is not needed, the safetyof the reaction is improved, the pollution caused by using a metal reagent is avoided, and the reaction cost is saved.

A FACILE ROUTE TO HOMOCHIRAL SULFOXIDES

Biocatalytic resolution of methyl sulfinylacetates afford sulfoxides (R)-(1)-(6) in very high optical yields; the products have been used in a systematic study of the "SPAC" reaction, an asymmetric synthesis of γ-hydroxy-α,β-unsaturated esters.