1257063-95-8

Basic information

• Product Name: 4-oxo-2-phenyl-7-[4-(trifluoromethyl)phenyl]-4H-chromen-8-yl trifluoromethanesulfonate
• Synonyms: 4-oxo-2-phenyl-7-[4-(trifluoromethyl)phenyl]-4H-chromen-8-yl trifluoromethanesulfonate
• CAS NO: 1257063-95-8
• Molecular Weight: 514.402
• Mol File: 1257063-95-8.mol
• Article Data: 2

Chemical Properties

• CAS DataBase Reference: 4-oxo-2-phenyl-7-[4-(trifluoromethyl)phenyl]-4H-chromen-8-yl trifluoromethanesulfonate(CAS DataBase Reference)
• NIST Chemistry Reference: 4-oxo-2-phenyl-7-[4-(trifluoromethyl)phenyl]-4H-chromen-8-yl trifluoromethanesulfonate(1257063-95-8)
• EPA Substance Registry System: 4-oxo-2-phenyl-7-[4-(trifluoromethyl)phenyl]-4H-chromen-8-yl trifluoromethanesulfonate(1257063-95-8)

Safety Data

• Hazardous Substances Data: 1257063-95-8(Hazardous Substances Data)

Upstream product

• 38183-03-8 7,8-dihydroxyflavone 
• 1257063-84-5 4-oxo-2-phenyl-4H-chromene-7,8-diyl Bis(trifluoromethanesulfonate) 
• 128796-39-4 4-trifluoromethylphenylboronic acid 

Relevant articles and documents

Efficient synthesis of arylated flavones by site-selective Suzuki-Miyaura cross-coupling reactions of the bis(triflate) of 5,7- and 7,8-dihydroxyflavone

Suzuki-Miyaura reactions of the bis(triflate) of 5,7- and 7,8-dihydroxyflavone proceed with very good site selectivity in favor of position 7 and allow the synthesis of various arylated flavones. The reaction of 5,7-dihydroxyflavone with one equivalent of triflic anhydride also proceeds with very good site selectivity in favor of position 7. The subsequent Suzuki-Miyaura reaction of the product allows the synthesis of 7-aryl-5-hydroxyflavones. The regioselectivity is discussed based on DFT calculations.