1257106-74-3 Usage
Type of compound
Salt form of 1-(pyrimidin-4-yl)ethanamine
Parent compound
Pyridine
Usage
Research chemical in medicinal chemistry and pharmaceuticals
Therapeutic properties
Anti-inflammatory and neuroprotective effects
Potential applications
Treatment of neurological disorders (e.g., Alzheimer's disease, Parkinson's disease)
Significance
Shows promise in medical research and development of new pharmaceutical drugs
Check Digit Verification of cas no
The CAS Registry Mumber 1257106-74-3 includes 10 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 7 digits, 1,2,5,7,1,0 and 6 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 1257106-74:
(9*1)+(8*2)+(7*5)+(6*7)+(5*1)+(4*0)+(3*6)+(2*7)+(1*4)=143
143 % 10 = 3
So 1257106-74-3 is a valid CAS Registry Number.
1257106-74-3Relevant articles and documents
A four-step synthesis of novel (S)-1-(heteroaryl)-1-aminoethanes from (S)-Boc-alanine
?enica, Luka,Petek, Nejc,Gro?elj, Uro?,Svete, Jurij
, p. 60 - 71 (2015)
A series of (S)-1-(pyrimidin-4-yl)-, and regioisomeric (S)-1-(pyrazolo[1,5-a]pyrimidin-7-yl)-, and (S)-1-(pyrazolo[1,5-a]pyrimidin-5-yl)-1-aminoethanes were prepared by cyclisation of (S)- N-Boc-alanine-derived ynone with N,N-1,3-dinucleophiles, such as amidines and α-aminoazoles, followed by acidolytic removal of the Boc group. Stereoselective catalytic hydrogenation of (S)-1-(pyrazolo[1,5-a]pyrimidin-7-yl)-1-aminoethanes lead to saturation of the pyrimidine ring to afford ～4:1 mixture of diastereomeric 4,5,6,7-tetrahydropyrazolo[1,5-a]pyrimidines. The structures of novel compounds were elucidated with NMR spectroscopy.
